Senior/Principal Scientist, Protein Production
We are a pioneering, stealth-stage biotechnology company seeking to create enzymatic solutions to unmet challenges in medicine. Our proprietary protein evolution platform, developed in the lab of Prof. David Liu, enables us to rapidly generate novel proteases with high specificity and potency for user-defined therapeutic targets. By reprogramming the specificity of proteases, we aim to revolutionize the treatment of protein-driven diseases. World class scientific founders David Liu (Broad, Harvard), Min Dong (Boston Children’s Hospital, Harvard), Jim Wells (UCSF), and Travis Blum (Broad, Harvard) and backing from leading life science venture capital firms including Atlas, Arch, F-Prime, GV, and Newpath, come together in a dynamic start-up environment.
The Senior/Principal Scientist – Protein Production will be responsible for design of constructs, expression, purification, and QC of our novel protease therapeutics and associated reagents from microbial or mammalian cell culture. This includes design and optimization of expression constructs, expression and purification of proteins from pilot to scale-up, and QC including analytical SEC, SDS-PAGE, endotoxin assessment, and other properties as needed. Purification strategies may include size exclusion, affinity, ion-exchange, and other chromatography techniques using an AKTA FPLC system or other methods.
We recognize the value of diversity in our workforce and are committed to equal opportunity. We consider all qualified employment applicants without regard to race, religion, color, gender, age, national origin, sexual orientation, gender identity, partnership status, protected veteran status, disability, or any other status protected by federal, state, or local law. Individuals who hold legal work authorization applicable to employment in the United States will be considered without regard to citizenship/alienage.
We are not accepting unsolicited resumes from employment agencies for any employment opportunities.