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Principal Associate Scientist/Scientist, Flow Cytometry Assay Development

Seattle, WA

About GentiBio 

GentiBio is an emerging biotherapeutics company co-founded by pioneers in Treg biology and synthetic immunology from Seattle Children’s Research Institute, Benaroya Research Institute, and MIGAL Galilee Research Institute. GentiBio is focused on the development of EngTregs programmed to treat autoimmune, alloimmune, autoinflammatory and allergic diseases. GentiBio’s proprietary autologous and allogeneic EngTregs platform integrates key complementary technologies needed to successfully restore immune tolerance and overcome major limitations in existing regulatory T-cell therapeutics. 

GentiBio is seeking to build an organization with an exceptional company culture focused on empowerment, care for our team members, an appreciation for diversity and inclusion, and the development of our people. As such, we are looking for candidates who are not just great scientists and business professionals, but individuals who are looking to contribute to building and modeling an outstanding company culture – and having fun while doing so. 

GentiBio is building corporate operations in both Boston and Seattle. We are looking for outstanding leaders and scientists to join our team in both of our locations. 

Job Summary

GentiBio is seeking a self-driven, collaborative, results-oriented, and creative Principal Associate Scientist/Scientist to join our Analytical Development (AD) team in Seattle. The successful candidate will develop and qualify flow cytometry methods in support of GentiBio’s first engineered regulatory T-cells (EngTregs) program. This lab-based role offers exposure to multiple facets of departmental and organizational build, leadership, technological growth, and an ample opportunity to be a high impact trailblazer in the emerging field of regulatory T-cell therapy

Job Responsibilities

  • Foster the culture of seeking and giving help, inclusion, authenticity, and fun
  • Develop flow cytometry methods in line with the needs of the product and the end-user to support EngTreg drug product release and characterization
  • Qualify methods as per regulatory guidance and document in qualification reports
  • Create method SOPs and support method transfer to the clinical manufacturing facility
  • Partner with Process Development, Research, and Translational teams to align on the key EngTreg product attributes and best approaches to measuring them
  • Collaborate with peers in Analytical Development to ensure that prioritized activities (i.e., method development, qualification, sample testing, etc.) are completed to a high standard and on time
  • Actively contribute with cross-functional teams by sharing technical expertise and experiences and effectively communicating results
  • Participate as a flow cytometry subject matter expert in investigations as needed
  • Help build the cell therapy development laboratory from lab layout to mapping out of analytical workflows
  • Contribute technical expertise to new technology and due diligence efforts as needed

Qualifications and Education Requirements

  • B.S./M.S. in a relevant Science or Engineering discipline with 6+ years, or Ph.D. with 0-2 years of relevant experience
  • Expertise in multi-color flow cytometry and experience developing methods
  • Knowledge of Treg biology preferred but not required
  • Experience with statistical data analysis and CMC regulatory filings preferred but not required
  • Exceptional teamwork and communication skills
  • Flexibility to pivot from plan A to plan B
  • Ability to synthesize complex information and focus on key deliverables
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