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Associate Scientist/Senior Associate Scientist, R&D Molecular Biology

Boston, MA

About GentiBio
GentiBio is an emerging biotherapeutics company co-founded by pioneers in Treg biology and synthetic immunology from Seattle Children’s Research Institute, Benaroya Research Institute, and MIGAL Galilee Research Institute. GentiBio is focused on the development of EngTregs programmed to treat autoimmune, alloimmune, autoinflammatory and allergic diseases. GentiBio’s proprietary autologous and allogeneic EngTregs platform integrates key complementary technologies needed to successfully restore immune tolerance and overcome major limitations in existing regulatory T-cell therapeutics.

GentiBio is seeking to build an organization with an exceptional company culture focused on empowerment, care for our team members, an appreciation for diversity and inclusion, and the development of our people. As such, we are looking for candidates who are not just great scientists and business professionals, but individuals who are looking to contribute to building and modeling an outstanding company culture – and having fun while doing so.

GentiBio is building corporate operations in both Boston and Seattle. We are looking for outstanding leaders and scientists to join our team in both of our locations.

Job Summary
GentiBio is seeking a motivated Associate Scientist to join our vector production team and help advance platform engineering to support GentiBio’s cell therapy programs. The successful candidate will report to the Senior Scientist leading the core and support the development of engineered Treg cells by employing cutting-edge molecular techniques to design, create, and validate DNA constructs. We are searching for enthusiastic individuals who are passionate about working at the bench to advance programs and solve technical challenges. This role offers ample opportunity for learning and growth.

Job Responsibilities

  • Foster the culture of seeking and giving help, inclusion, authenticity, and fun
  • Perform and troubleshoot molecular cloning to support company objectives
  • Prepare plasmid stocks, perform quality control of plasmid DNA, and maintain records for the plasmid database
  • Extract DNA/RNA from cells/tissues, perform PCR-based assays, and assist as needed with viral vector production
  • Help establish protocols and research capabilities
  • Maintain electronic lab notebooks and communicate results to the scientific team
  • Work independently and collaborate with scientific colleagues in support of team goals
Qualifications and Education Requirements
  • BS/MS (non-PhD role) in molecular biology or related field with 1+ years of molecular biology and cloning experience 
  • Hands-on experience with molecular biology techniques, including plasmid/genomic DNA purification, primer design, cloning (e.g., traditional, Golden Gate, Gibson assembly), PCR, and gel electrophoresis
  • Familiarity with SnapGene and/or CLC Main workbench preferred
  • Excellent communication and organizational skills, with an ability to embrace change and multi-task in a fast-growing environment
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