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Scientist, Immunology

Boston, MA

About GentiBio
GentiBio is an emerging biotherapeutics company co-founded by pioneers in Treg biology and synthetic immunology from Seattle Children’s Research Institute, Benayroya Research Institute, and MIGAL Gaililee Research Institute. GentiBio is focused on the development of EngTregs programmed to treat autoimmune, alloimmune, autoinflammatory and allergic diseases. GentiBio’s proprietary autologous and allogeneic EngTregs platform integrates key complimentary technologies needed to successfully restore immune tolerance and overcome major limitations in existing regulatory T-cell therapeutics.

GentiBio is seeking to build an organization with an exceptional company culture focused on empowerment, care for our team members, an appreciation for diversity and inclusion, and the development of our people. As such, we are looking for candidates who are not just great scientists but individuals who are looking to contribute to building and modeling an outstanding company culture – and having fun while doing so.

GentiBio is building corporate operations in both the Boston and Seattle. We are looking for outstanding leaders and scientists to join our team in both of our locations.

Job Summary
GentiBio is seeking a motivated Scientist to join our exciting, fast growing, and well financed team to develop novel cell therapies for autoimmune diseases. This individual will report to the Senior Scientist leading the early development programs, and help the team to engineer and evaluate indication-specific EngTregs in vitro and in vivo. In this position, the candidate will have the opportunity to utilize cutting-edge cellular and molecular techniques to generate the next generation of cell therapies for autoimmune diseases, with high visibility to the senior leadership team.

Job Responsibilities

  • Independently design and execute proof-of-concept experiments in vitro and in vivo
  • Handle execution of experiments, data collection, and interpretation of the results
  • Isolate, culture, engineer, and characterize gene-edited primary mouse and human immune cells
  • Generate data and document results in an electronic lab notebook
  • Present data at internal meetings and select conferences
  • Contribute proactively to cross-functional activities across research groups and with other departments as needed

Qualifications and Education Requirements

  • Strong background in immunology with a PhD in Immunology or related discipline with 0-2 years of industry experience
  • Hands-on experience with primary mouse or human cell culture
  • Extensive experience with current immunology techniques such as multicolor flow cytometry, ELISA, and cell culture-based assays
  • Experience with molecular biology, such as cloning, ddPCR, and NGS
  • Experience with viral- and non-viral genome engineering techniques
  • Ability to work in a fast-paced environment and adapt to changes
  • Exceptional teamwork and communication skills
  • Demonstrated experience in working within a team environment
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