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Scientist, Autoimmunity

Cambridge, MA · Science/Research
Company Description

Rubius Therapeutics is a clinical-stage biopharmaceutical company developing a new class of medicines called Red Cell Therapeutics™. Our proprietary RED PLATFORM® was designed to genetically engineer and culture Red Cell Therapeutics™ that are selective, potent and off-the-shelf allogeneic cellular therapies for the potential treatment of several diseases across multiple therapeutic areas. Our therapies can potentially be used to kill tumors in cancer and to regulate the immune system for the treatment of autoimmune diseases. Our IND for RTX-240, our first oncology candidate for the treatment of solid tumors, has been cleared by the FDA. Additionally, we plan to file an IND for RTX-321 for the treatment of HPV-positive tumors by year-end.

We are proud of our passionate, high-performance culture – one based on a set of values that are the cornerstone of who we are and how we hold ourselves accountable. Founded in 2013, we are based in Cambridge, MA and currently expanding across all functions within the organization. Red blood cells are no longer just for carrying oxygen. Check us out at www.rubiustx.com, or follow us on Twitter and LinkedIn or like us on Facebook.

Job Summary

We are looking for a Scientist to join our Autoimmune group to help drive key autoimmune programs. The candidate must be independent, goal-oriented, technically competent, and able to efficiently work across multiple projects. We are searching for enthusiastic, innovative, and highly motivated individuals, with a deep scientific background in immunology, preferably autoimmune diseases, who are comfortable working in a fast-paced entrepreneurial environment.

  • Work closely with a team of scientists in the Discovery teams to drive key autoimmune projects.
  • Design and execute experiments for non-routine in vitro immune assays, in vivo studies, and ex vivo assays.
  • Phenotyping immune populations, sample preparation for in vivo studies, sample analysis.
  • Independent data analysis and proper electronic notebook record keeping.
  • Communication of experimental plans and data to multiple cross-functional scientific teams.
  • Support the continued protection, creation, and expansion of the company’s intellectual property.
  • Assist in maintaining a strong, entrepreneurial, and creative culture with a clear sense of urgency and focus on providing transformational therapies to patients.
Qualifications & Education
  • Ph.D. degree in biology, immunology, biochemistry, bioengineering or related discipline, and 2+ years of relevant laboratory experience, pharmaceutical or biotechnology industry preferred.
  • Deep knowledge of immunology, preferably DC and T cell biology, and a systematic approach to understanding inflammatory and tolerance molecular mechanisms.
  • Research background in autoimmune disease.
  • Strong experimental skills, including tissue culture, isolation, and culture of primary immune cells, primary immune cell assays, flow cytometry, ELISA, and in vivo model development.
  • Passionate about working at the bench to independently contribute to research directions and solve challenging issues.
  • Detail-oriented, self-motivated, and comfortable working with highly technical projects and personnel.
  • Ability to work on multiple projects simultaneously and deliver conclusive results.
  • Highly adaptable and responsive to delivering for challenging commitments.
  • Effective written and oral communication skills.
  • Team-oriented with a strong work ethic.
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