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Scientist/Senior Scientist, Bioinformatics & Computational Biology

Boston, MA
Ascidian Biotherapeutics is a biotech startup that uses a unique molecular technology to unlock gene therapy.  Gene therapy is entering a new era, as the scientific community continuously pushes the field forward. But current technologies cannot overcome the challenges of many diseases. Ascidian’s unique approach aims to unlock these doors and in doing so, enable treatment for millions of patients worldwide. Ascidian is located in Boston within the brand new SmartLabs facility at 40 Guest St. in Boston, MA.
 
We are seeking a Bioinformatician / Computational Biologist / RNA Biologist, to be based in our Boston-area location, who will:
  • Design: translate ideas into libraries of nucleic acid sequences
  • Evaluate: assess whether those ideas work through analysis of NGS data
  • Repeat: based on the data, originate new ideas that can be tested in the next cycle
 
General Requirements:
  • Ph.D in Bioinformatics, Biology, or related discipline
  • Ability to independently determine what questions to ask about an NGS dataset
  • Ability to interrogate processed NGS data through plotting and statistical analysis 
  • Ability to work collaboratively in a team environment with biologists and computational biologists
  • Ability to design and interpret experimental data in the context of biology 
  • Outstanding communication and presentation skills (verbal and written)
  • Ability to code in R
  • Experience with functional genomic methods such as RNA-seq, ChIP-Seq, Ribosome profiling, and Massively Parallel Reporter Assays
 
Additional skills/experience beneficial, but not required:
  • Postdoctoral experience in bioinformatics or biology
  • Fluency in cloud computing, Matlab, Perl/Python, Unix
  • Fluency in other programming language and databases, e.g. C++, Java, SQL
  • Experience conducting biological (wet-lab) experiments (e.g. PCR, RNA-seq library preparation, protein analysis)
If you feel energized by what you read here, but aren’t sure you meet every requirement, please consider applying! We believe diverse backgrounds lead to innovative thinking that enables effective treatment for millions of patients. Above all, we’re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.
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